diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 15bfd5ef475548401d5ac7cd11c8eaec9eac5f63..2fe035f6cba4581e91c055cdc966a0e7122e2bae 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/Felix/Configuration.h b/Marlin/example_configurations/Felix/Configuration.h
index 36c1239da8397b0f404647821d48fbc5a8fd22ba..f8c84739d9a4dd0afcf3724ff4a9c5c3175455f5 100644
--- a/Marlin/example_configurations/Felix/Configuration.h
+++ b/Marlin/example_configurations/Felix/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/Felix/DUAL/Configuration.h b/Marlin/example_configurations/Felix/DUAL/Configuration.h
index 55e068957ab1b6c4591486125ce5117d6081cce2..db8d390c667d3c5305d667d604ce266cdccab118 100644
--- a/Marlin/example_configurations/Felix/DUAL/Configuration.h
+++ b/Marlin/example_configurations/Felix/DUAL/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 2
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/Hephestos/Configuration.h b/Marlin/example_configurations/Hephestos/Configuration.h
index d5b6ed0b2495a1b084433870b1c532638d6f6fdd..e2bb15834a41c7e9da31f5262ee0407f383120f7 100644
--- a/Marlin/example_configurations/Hephestos/Configuration.h
+++ b/Marlin/example_configurations/Hephestos/Configuration.h
@@ -123,6 +123,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/Hephestos_2/Configuration.h b/Marlin/example_configurations/Hephestos_2/Configuration.h
index 7b9849bacb6fc56dde111da5b8deed41cbcd8fe0..daf41cfbf43782e4ae2e708b955a008bbccd518a 100644
--- a/Marlin/example_configurations/Hephestos_2/Configuration.h
+++ b/Marlin/example_configurations/Hephestos_2/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/K8200/Configuration.h b/Marlin/example_configurations/K8200/Configuration.h
index e99d4dd01a62d53808350e34f37bcb2ea831d032..9037af19f5b11105dd2ee096c6d1adeda26a0a96 100644
--- a/Marlin/example_configurations/K8200/Configuration.h
+++ b/Marlin/example_configurations/K8200/Configuration.h
@@ -127,6 +127,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h b/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
index 2d3067c6d7dad4ef852bfb57a73a90db19bc4ec0..b145d9a5a7e7dd216cfbe7f5888d00fbfe3249e7 100644
--- a/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
+++ b/Marlin/example_configurations/RepRapWorld/Megatronics/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/RigidBot/Configuration.h b/Marlin/example_configurations/RigidBot/Configuration.h
index d1522c3fa7e49b18d440c0db8e798b841506d998..2768283416008301b69bbeb6d025af728ee8fd0e 100644
--- a/Marlin/example_configurations/RigidBot/Configuration.h
+++ b/Marlin/example_configurations/RigidBot/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1  // Single extruder. Set to 2 for dual extruders
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/SCARA/Configuration.h b/Marlin/example_configurations/SCARA/Configuration.h
index 13c484ac1f09823b7dc974d026e53a9ba049da54..522760893d7bf5fc6af65fec81df48493dd09cc2 100644
--- a/Marlin/example_configurations/SCARA/Configuration.h
+++ b/Marlin/example_configurations/SCARA/Configuration.h
@@ -145,6 +145,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/TAZ4/Configuration.h b/Marlin/example_configurations/TAZ4/Configuration.h
index 0da46efdd8ef064c60a25071fc5f95bee116693b..cebbcc137c1b1af7e2054d0ee6f87c90b100091f 100644
--- a/Marlin/example_configurations/TAZ4/Configuration.h
+++ b/Marlin/example_configurations/TAZ4/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/WITBOX/Configuration.h b/Marlin/example_configurations/WITBOX/Configuration.h
index ae59c5d15c1f9ee9395c0a07666a8d851b10d9d8..8553ac700394058fa71b958e1bebf2b77651a45a 100644
--- a/Marlin/example_configurations/WITBOX/Configuration.h
+++ b/Marlin/example_configurations/WITBOX/Configuration.h
@@ -123,6 +123,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/adafruit/ST7565/Configuration.h b/Marlin/example_configurations/adafruit/ST7565/Configuration.h
index 638ce4032e3fea5a25cef613fd95d5f697a3426e..b1f19d42a6c525ebf82fa0b54983230d8141699d 100644
--- a/Marlin/example_configurations/adafruit/ST7565/Configuration.h
+++ b/Marlin/example_configurations/adafruit/ST7565/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/delta/biv2.5/Configuration.h b/Marlin/example_configurations/delta/biv2.5/Configuration.h
index 4560cd8b93be3058a7f345a88bc29832f776be11..55f99dc410fb6251e87209f7bb402504d0e0feea 100644
--- a/Marlin/example_configurations/delta/biv2.5/Configuration.h
+++ b/Marlin/example_configurations/delta/biv2.5/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 2
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/delta/generic/Configuration.h b/Marlin/example_configurations/delta/generic/Configuration.h
index e2e9227b37f679954b78523ed7f8b251a10103d1..b92ee7daecf362cd7a69d9796febea2a97ffa15c 100644
--- a/Marlin/example_configurations/delta/generic/Configuration.h
+++ b/Marlin/example_configurations/delta/generic/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/delta/kossel_mini/Configuration.h b/Marlin/example_configurations/delta/kossel_mini/Configuration.h
index 4729e39be3e795054f2ab4cfd0ad7096960d8bfc..080268d6b6f43b54aaa50af35aba7dfe5e228951 100644
--- a/Marlin/example_configurations/delta/kossel_mini/Configuration.h
+++ b/Marlin/example_configurations/delta/kossel_mini/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/delta/kossel_pro/Configuration.h b/Marlin/example_configurations/delta/kossel_pro/Configuration.h
index a37bced783ea07695757e7f159a8a8909a83b353..3f98ab105a34135c91c0fc1a898aba0faedc1d07 100644
--- a/Marlin/example_configurations/delta/kossel_pro/Configuration.h
+++ b/Marlin/example_configurations/delta/kossel_pro/Configuration.h
@@ -126,6 +126,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/delta/kossel_xl/Configuration.h b/Marlin/example_configurations/delta/kossel_xl/Configuration.h
index c23b546ab2d04cbda2a9429faf7c47ae30d589b3..8af8a844ef0fb1d4f1e14f6bce74e805c9482c09 100644
--- a/Marlin/example_configurations/delta/kossel_xl/Configuration.h
+++ b/Marlin/example_configurations/delta/kossel_xl/Configuration.h
@@ -113,6 +113,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/makibox/Configuration.h b/Marlin/example_configurations/makibox/Configuration.h
index db34f1ab00b3e4804cc0bd1f9277db37f8c4c51c..bc5c1317fea9eeeee8231ce8ba402698bba08129 100644
--- a/Marlin/example_configurations/makibox/Configuration.h
+++ b/Marlin/example_configurations/makibox/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.
diff --git a/Marlin/example_configurations/tvrrug/Round2/Configuration.h b/Marlin/example_configurations/tvrrug/Round2/Configuration.h
index 9e85c919d8a986b243dae4c18a6aa395d1748315..eb3759e37852058b5e84124181b312b1620876e9 100644
--- a/Marlin/example_configurations/tvrrug/Round2/Configuration.h
+++ b/Marlin/example_configurations/tvrrug/Round2/Configuration.h
@@ -120,6 +120,9 @@
 // :[1,2,3,4]
 #define EXTRUDERS 1
 
+// For Cyclops or any "multi-extruder" that shares a single nozzle.
+//#define SINGLENOZZLE
+
 // Offset of the extruders (uncomment if using more than one and relying on firmware to position when changing).
 // The offset has to be X=0, Y=0 for the extruder 0 hotend (default extruder).
 // For the other hotends it is their distance from the extruder 0 hotend.